Faithful DNA replication is essential for cell survival and genome stability. However, DNA replication faces continual challenges from DNA damage, as well as intrinsic and extrinsic stressors. For ...
Fig. 4: The process of establishment of pre-RCs at an S. cerevisiae origin in which the B2 domain is separated from the A and B1 origin elements. This Review focuses on the first step in eukaryotic ...