Several bacteria from the Clostridium genus produce botulinum neurotoxins—the most potent biological toxins known—that cause botulism by blocking neurotransmitter release from nerves. Typically, the ...

UPTON, NY -- By deciphering the near atomic-level structure of the catalytic domain of botulinum toxin type E -- one of seven neurotoxins that cause botulism, a disease that paralyzes victims by ...

Researchers at Stockholm University have succeeded in creating a molecular blueprint of how one of the world's most dangerous toxins, botulinum toxin, is structured, stabilized, delivered and released ...

The toxin complex with its 14 components. The toxin itself is colored pink and sits at the top of the complex. The structure consists of tens of thousands of atoms, and here we only show the surface ...

In a comprehensive research study, scientists have uncovered a previously unknown mechanism explaining how neurons survive botulinum neurotoxin type A (BoNT/A) exposure, despite the toxin's powerful ...

The toxin behind two outbreaks in seven months is hard to find—and just a handful of labs are equipped to look for it at all ...

Botulinum neurotoxin (BoNT) is responsible for botulism, a clinical condition resulting in flaccid muscle paralysis and potentially death. The light chain is responsible for its intracellular toxicity ...

Botulinum toxin (BTX) injection could relieve many disorders in the maxillofacial regions. Although it could have some side effects on bones and muscles. This study investigated the effects of a ...

Researchers have identified genes encoding a previously undiscovered version of the botulinum neurotoxin in bacteria from a cow’s gut. Researchers from the Quadram Institute have identified genes ...

The Botox injections that smooth wrinkles rely on the ability of botulinum toxins from the bacterium Clostridium botulinum to block communication between cells. In the cosmetic treatment, these toxins ...