For decades, cancer immunotherapy has focused primarily on CD8 + cytotoxic T lymphocytes as the main executors of tumor cell killing. However, growing clinical and single-cell sequencing evidence ...

Detailed mapping of CD4⁺ T cells from children with systemic lupus erythematosus (SLE) has revealed distinct immune cell subsets with likely roles in disease pathogenesis, according to a study led by ...

A landmark study due to start in the coming months aims to test a method for rejuvenating our immune system in older age. The ...

As high-parameter T-cell profiling becomes increasingly central to translational research and biomarker discovery, there is ...

Immune cells called double negative T cells are abundant in the intestine but have been poorly understood till date. In a recent study, researchers from the Institute of Science Tokyo report that ...

For some people, cancer immunotherapies are life-changing. These treatments can turn the body's own immune system against a tumor, either eliminating it or shrinking it enough to make surgery possible ...

New vaccine ‘could rejuvenate aging immune systems to tackle cancer and dementia’ - Researchers hope that resetting these cells may help the immune system regain characteristics of healthier immune ...

A research team from the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Bloomberg School of Public Health has discovered how the ...

Abnormal expansion of PD-1+ T lymphocytes may be a sign of lupus nephritis onset in patients with SLE. Elevated PD-1+CD4+ T cells represent an independent risk factor for lupus nephritis (LN) and may ...

For the immune system to effectively combat pathogens, antibody responses must be precisely controlled. So-called follicular ...