As many as 1 in 4 cancers are driven by mutations in the SWI/SNF chromatin-remodeling complex, which controls access to DNA.

Bcl-3 is an atypical member of the IκB family that plays a critical role in modulating the NF‐κB transcriptional programme. Unlike classical inhibitors that sequester NF‐κB in the cytoplasm, Bcl-3 ...

New York, NY—In the Great Hall of the Cunard Building, deep in Lower Manhattan, members of the Cancer Research Institute (CRI), a nonprofit that supports the discovery and development of cancer ...

Cancer cells are metabolic opportunists, bending every pathway to fuel unchecked growth. Now UCLA scientists show that a single protein—Insulin-like Growth Factor 2 mRNA-Binding Protein 3 ...

A research team at KAIST has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation ...

A well-known diabetes drug may have a previously overlooked effect on the body’s metabolism.

Fox Chase researchers use 3D genomic testing to improve lymphoma and sarcoma diagnosis and treatment by revealing tumor cell ...

Saliva IL6 Upregulation As a Potential Indicator of Tobacco-Smoke Associated OSCC and Disease Progression and the Association of Saliva RELA(p65) Upregulation With OSCC Local Invasion in Non-Smokers ...

University of Navarra (Spain) researchers have developed RNACOREX, a new open-source software capable of identifying gene regulation networks with applications in cancer survival analysis. The tool, ...

The same cellular renewal that keeps our bodies healthy might also fuel the growth of cancer. A UC Merced biologist has found that the brain could hold the key to stopping it. Professor Néstor Oviedo, ...

Researchers from the University of Seville have participated in research to identify the molecular details of the regulation of an enzyme essential for sugar metabolism and closely linked to cell ...