The complement system, a central component of innate immunity, exerts a dual influence on cerebral ischaemia, driving both acute tissue injury and later reparative processes. Following arterial ...

(Left) Pre-ignition (below the activation threshold) Only a handful of immune “tags” (C3b proteins) cover the nanoparticle, so it barely sticks to the white membrane—too few contact points means the ...

White blood cells called neutrophils act as factories for C4A, linking peripheral immunity to schizophrenia and synaptic ...

While there is currently no cure for geographic atrophy, certain treatments, such as complement inhibitors, can help slow its progression by targeting immune system activity that damages the macula.

A collaborative team from the School of Engineering and Applied Science and the Perelman School of Medicine have unraveled the mathematics of a 500-million-year-old protein network that acts like the ...