Study authors evaluated whether using an observational study that includes Medicare claims data could detect the proarrhythmic risk of medications known to prolong the QT interval. The Medicare claims ...

Research confirms that grapefruit juice prolongs the QT interval; this finding has implications for patients taking medications that prolong the QT interval and may have implications for patients with ...

QT prolongation occurs when the heart muscle takes longer to contract and relax than usual. It can affect heart rhythms and lead to sudden cardiac arrest. The heart is a muscle that contracts and ...

LQT-1213 is a first-in-class serum glucocorticoid regulated kinase 1 inhibitor. The Food and Drug Administration (FDA) has granted Orphan Drug designation to LQT-1213, a first-in-class serum ...

Long QT syndrome is a leading cause of sudden death in young persons, with a prevalence exceeding 1 in 2000. It is characterized by prolongation of the QT interval, aberrant T-wave morphologic ...

Even with little evidence, hope exists both in the medical community and the public that hydroxychloroquine (or its close relative chloroquine) and the antibiotic azithromycin, all long-used ...

Grapefruit juice is already listed as a substance to avoid when taking QT-prolonging medications because it increases the toxicity of many drugs. Investigators have now confirmed the QT-prolonging ...