Researchers from the University of Barcelona and the August Pi y Sunyer Biomedical Research Institute (IDIBAPS) have shown that the IGFBP3 protein plays a relevant role in human lung development. The ...

Researchers have shown that the IGFBP3 protein plays a relevant role in human lung development. The results of the study, which used organoids derived from embryonic lungs, open up new perspectives on ...

Northwestern Medicine investigators have discovered that mitochondria regulate essential cellular signaling for the development of epithelial cells in the lungs, cells which are crucial for the ...

Single-cell technologies are redefining the molecular signatures of canonical cell types and identifying new cell types and cell states in organs and tissues 1,2. Specifically, single-cell RNA ...

The developing human lung has been mapped in unprecedented detail, identifying 144 cell states in the early stages of life, and uncovering new links between developmental cells and lung cancer. In ...

Drug development for lung diseases is complicated. Most clinical trials that test novel drugs fail due to the fact that laboratory models cannot accurately replicate human physiology. Currently ...

Immune cells play an active and intimate role in directing the growth of human lung tissue during development, researchers find, revolutionizing our understanding of early lung development and the ...

To demonstrate sensitivity of diffusion-weighted MRI (DW-MRI) to pulmonary cellular-space changes during normal in utero development using fetal rhesus macaques, compared to histological biomarkers.

How do the lungs develop after taking their first breaths outside the womb? What cellular events and changes early in life give rise to lung malfunction and disease? To help answer these questions, ...

Researchers of the University of Barcelona and the August Pi y Sunyer Biomedical Research Institute (IDIBAPS) have shown that the IGFBP3 protein plays a relevant role in human lung development. The ...

How do the lungs develop after taking their first breaths outside the womb? What cellular events and changes early in life give rise to lung malfunction and disease? To help answer these questions, ...