The frequent spread of certain cancers to lymph nodes often necessitates surgery or radiation therapy that damages the lymphatic system and can cause lymphedema, a condition of localized fluid ...

A new study from researchers at Uppsala University presents novel findings on why human lymph nodes lose their function with age and the consequences for the effectiveness of our immune system. The ...

These findings from research into diffuse large B cell lymphoma (DLBCL) are based on analyses of human patients and a murine model. The immunosuppressive role of fibroblastic reticular cells (FRCs) in ...

A recent paper in Nature Biomedical Engineering, by Dr. David J. Mooney demonstrated how a new vaccine can enhance and maintain lymph node function to boost immunity against cancer in mice. Mooney, a ...

Recently, a research team led by Prof. Jiang Liwei from the Institute of Health and Medical Technology, Hefei Institutes of Physical Science of Chinese Academy of Sciences (CAS), collaborated with ...

Lymph nodes are critical to the body's immune response against tumors but paradoxically, cancer cells that spread, or metastasize, to lymph nodes can often avoid being eliminated by immune cells.

Dramatic changes in lymphatic vessel contraction and in the lymph nodes that drain inflamed joints are associated with disease progression and response to therapy in murine models of rheumatoid ...

Lymphatic growth (lymphangiogenesis) within lymph nodes functions to promote dendritic cell entry and effector lymphocyte egress in response to infection or inflammation. Here we demonstrate a crucial ...

Vaccines trigger a notably rapid response in the stromal cells of draining lymph nodes within the first hours after administration. Researchers at the University of Turku and the InFLAMES Flagship in ...

If we imagine our immune system to be a police force for our bodies, then previous work has suggested that the Lymph nodes would be the best candidate structures within the body to act as police ...

Lymph node metastasis occurs in "metastatic" lymph nodes, lymph nodes that contain cancer cells that have spread from elsewhere in the body. A part of the immune system, lymph nodes are tiny ...