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Gene therapy corrects untreatable cystic fibrosis mutation in lab tests

Researchers at the University of Trento have developed a CRISPR-based adenine base editing therapy that repaired the ...
Morning Overview on MSN

Gene therapy targets rare cystic fibrosis mutation affecting ~10%

For roughly one in ten people living with cystic fibrosis, the drugs that have transformed survival for most CF patients are ...

The Lab Catches Up to the Clinic: How Functional Precision Oncology Goes Beyond Genomics

For decades, oncologists have had a powerful but imperfect ally in the fight against cancer: genomic testing. The ability to ...

Lab-grown mini-brains shed light on childhood epilepsy

Why does the same genetic mutation cause a severe brain malformation in some patients but not in others? Researchers from the ...

Base editing repairs mutation and liver function in mouse model of Zellweger spectrum disorder

In 2025, baby KJ Muldoon became the first person to receive a personalized gene editing treatment, which likely saved his ...
EurekAlert!

In mice, gene editing repairs a mutation that causes rare liver disorder

Scientists have corrected an extremely rare and life-threatening genetic disease of the liver in mouse models and human ...
Technology Networks

How Cells With Cancer-Causing Mutations Corrupt the Local Environment

Researchers uncover how mutant lung cells reshape surrounding tissue through signaling loops with fibroblasts and immune ...
Nature

Experimental Evolution of Escherichia Coli and Adaptive Mutations

The study of experimental evolution in Escherichia coli has provided unprecedented insights into the mechanisms of adaptive mutations, elucidating how populations diverge and optimise their fitness ...