In this article we are going to talk about the very basic concept and before that the terminologies we are using in the organic chemistry especially in reaction mechanism. We all know the chemical ...

Cross-electrophile coupling reactions have emerged as a transformative approach in organic synthesis, enabling the direct formation of carbon–carbon bonds between two electrophilic partners without ...

Chemists are amped up about two new reactions that use electricity to form different types of carbon-carbon bonds. One transformation builds sp 3-sp 3 C–C bonds and the other creates sp 2-sp 3 C–C ...

In general, an electrophile is a highly reactive compound that "seeks" to bond with atoms or other molecules that have an available electron pair. In the buzzing hive of activity that is the cell, ...

The ability of covalent drugs to form strong bonds to protein targets tends to give them the advantage of long-lasting action. So far, covalent drug discovery has almost exclusively involved ...