Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without affecting depolarization-induced calcium release. The ...

The type 1 ryanodine receptor (RyR1) is an important calcium release channel in skeletal muscles essential for muscle contraction. It mediates calcium release from the sarcoplasmic reticulum, a ...

Researchers at Imperial College London have discovered that specialist macrophages—a type of white blood cell—play a key role in the control of muscle contraction and locomotion. The discovery ...

New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these ...

Supplements are generally not necessary for healthy individuals who can get their nutrients from diet. However, they are ...

When most people hear “calcium,” they immediately think of strong bones and teeth. While this connection is certainly valid, calcium carbonate’s benefits extend far beyond skeletal support. This ...