Metastatic neuroblastoma is an aggressive childhood cancer of neural crest origin. Stathmin, a microtubule destabilizing protein, is highly expressed in neuroblastoma although its functional role in ...
Researchers discovered that a protein called Stathmin-2 is lost in these neurons, which prevents them from regenerating after injury and disrupts their connection with the muscles to control movements ...
Survival with nivolumab therapy in recurrent/advanced squamous cell head and neck carcinoma. A single center experience. This is an ASCO Meeting Abstract from the 2018 ASCO Annual Meeting I. This ...
Scientists have a new clue about the roots of fear. This fear factor doesn't go bump in the night. Instead, it's a gene -- the stathmin gene, to be precise. Mice without that gene behave differently ...
Association of TS and ERCC1 mRNA expressions with overall survival in patients enrolled in CONFIRM 1 and 2. Background: Microtubule associated proteins (MAPs) endogenously regulate microtubule ...
A multi-institutional research team has suggested that aberrant TDP-43 processing of the pre-mRNA of a microtubule-associated protein, stathmin-2 (STMN2), may be the primary contributor to amyotrophic ...
Researchers use a DNA designer drug to restore key protein levels in motor neurons, delaying paralysis in a mouse model of ALS. In virtually all persons with amyotrophic lateral sclerosis (ALS) and in ...
Scientists may have found a gene for fear, a gene that controls production of a protein in the region of the brain linked with fearful responses. Their finding, published on Thursday, could lead to ...
Scientists have created a brave mouse that may eventually help scientists understand fearful people. Gleb Shumansky of Rutgers University in Piscataway, N.J., says a typical mouse tends to hug the ...