Cells have evolved careful checks to ensure DNA is copied only once, but how they switch on replication at the right moment ...

They were hardly modest, these two brash young scientists who in 1953 declared to patrons of the Eagle Pub in Cambridge, England, that they had "found the secret of life." But James Watson and Francis ...

Computational chemists at the University of Amsterdam's Van 't Hoff Institute for Molecular Sciences have developed a ...

Synthetic DNA motifs form the basis of nucleic acid nanotechnology. The biochemical and biophysical properties of these motifs determine their applications. Here, we present a detailed ...

DNA aptamers are powerful molecular tools in biosensing, bioimaging and therapeutics. However, a limited understanding of their tertiary structures and binding mechanisms hinders their further ...

An important specialty in this field—and a signature area of study at the University at Albany's RNA Institute—is DNA nanotechnology, wherein the base pairs that comprise DNA molecules are manipulated ...

PARP1 detection of DNA strand breaks allosterically leads to PARP1 synthesis of poly(ADP-ribose) modifications that signal DNA damage. HPF1 engages activated PARP1 to control modification site ...

New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...

In one sentence: DNA origami is a self-assembly technique that folds a long single-stranded DNA molecule into precisely defined nanoscale shapes using hundreds of short, computer-designed staple ...

James Watson, the scientist who became famous for helping discover the structure of DNA in 1953 and notorious decades later for suggesting that Black people are intellectually inferior to whites, has ...

DNA's iconic double helix does more than "just" store genetic information. Under certain conditions it can temporarily fold into unusual shapes. Researchers at Umeå University, Sweden, have now shown ...

The fixed idea that DNA is only a molecule that stores genetic information is being challenged. KAIST researchers have ...