Researchers at UT Southwestern Medical Center led a study to develop a computational method that reveals how immune cells ...

For some people, cancer immunotherapies are life-changing. These treatments can turn the body's own immune system against a ...

A first-in-human clinical trial of an immune rejuvenation therapy designed to restore the function of worn-out T cells is ...

Just as the human body relies on organs such as the heart, lungs and intestines to carry out specialized functions, cells contain organelles (‘little organs’) that carry out essential processes and ...

T cell exhaustion has been implicated in cancer and infectious diseases. In this study, we report a novel mouse model, “MolT-II”, with T cells expressing a transgenic T cell receptor (TCR) specific ...

Investigators led by Navdeep Chandel, Ph.D., the David W. Cugell, MD, Professor of Medicine in the Division of Pulmonary and Critical Care, have discovered how the metabolism of mitochondria supports ...

Scientists at Florida International University may have found a way to make a powerful cancer treatment work even better. The ...

Immunotherapy has transformed cancer care, offering a way to harness the body’s own immune system to fight tumors. But even with these advances, many patients still don’t respond. One major barrier to ...

A new Review reveals how aging can push the immune system into a paradoxical state, weaker against threats yet more prone to attacking the body’s own tissues.

Chimeric antigen receptor T cell (CAR-T) therapies have revolutionized treatment for various blood cancers. When traditional treatments fail, CAR-T therapies provide a second highly effective option.

The prevalence of autism spectrum disorder (ASD) is roughly one in 36 people, with a male-to-female ratio of 4:1. The disorder is known to be influenced by multiple factors, both genetic (gene ...