In 1977, two groups led by Richard Roberts and Phillip Sharp simultaneously observed the presence of “amazing [loop-like] sequence arrangements” in adenoviral DNA–RNA heteroduplexes, suggesting that ...
Pseudouridine (Ψ) is the most abundant RNA modification, yet studies of Ψ have been hindered by a lack of robust methods to profile comprehensive Ψ maps. Here we utilize bisulfite-induced deletion ...
In a recent study published in Nature, a group of researchers explored how the incorporation of N1-methylpseudouridine (1-methylΨ) into messenger ribonucleic acids (mRNAs) affects ribosomal ...
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