The DEAD-box RNA helicase (DDX) plays a central role in many aspects of RNA metabolism by remodeling the defined structure of RNA molecules. While a number of structural studies have revealed the ...
The Ebola virus causes a serious infection with a mortality rate between 50% and 90%. Nucleoproteins in the virus assemble into a helical arrangement and encapsulate a single stranded RNA genome, ...
There is an unmet need for new influenza vaccine strategies that compensate for impaired vaccine responses in elderly individuals. Here, we evaluated the effectiveness of a single-stranded RNA (ssRNA) ...
Class IV and class V viruses are single-stranded RNA (ssRNA viruses) in which the positive sense genome is translated into protein by host machinery, allowing viral reproduction. ssRNA class V viruses ...
Helping to make creation of nano-sized structures more user-friendly, scientists have designed single-stranded DNA and RNA (ssDNA and ssRNA) that can fold into desired shapes on command, and at an ...
Research reveals key differences between single- and double-stranded RNA, insights that may prove useful to fields from agriculture to medicine. Messenger RNA, or mRNA, has been in the news recently ...
Messenger RNA, or mRNA, has been in the news recently as a crucial component of the Pfizer-BioNTech and Moderna COVID-19 vaccines. The nucleic acid looks, for all intents and purposes, like a strand ...
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