Physicists introduce phase contrast to electron microscopy, delivering sharper images of our body's tiniest proteins

Nearly 100 years ago, a seemingly simple discovery revolutionized the microscope. The introduction of phase contrast, which ...
Nature

Improved image contrast in nonlinear light-sheet fluorescence microscopy using i\(^2\)PIE Pulse compression

Light-sheet fluorescence microscopy (LSFM) has allowed for faster three-dimensional imaging of biological samples with lower photo-bleaching and photo-toxicity than confocal microscopy 1. This is ...
The Scientist

Improvements In Light Microscopy Lead To New Applications

Hosts of new applications have turned the light microscope into an exquisitely sensitive measuring device that can be used to image dynamic cellular events right down to the molecular level. Indeed, ...
Nature

Smart hybrid microscopy for cell-friendly detection of rare events

Fluorescence microscopy offers unparalleled access to the spatial organization and dynamics of biological events in living samples, yet capturing rare processes over extended durations remains ...